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Apatinib suppresses the migration, invasion and angiogenesis of hepatocellular carcinoma cells by blocking VEGF and PI3K/AKT signaling pathways

Hepatocellular carcinoma (HCC) is a commonly diagnosed malignancy worldwide with poor prognosis and high metastasis and recurrence rates. Although apatinib has been demonstrated to have potential antitumor activity in multiple solid tumors, the underlying mechanism of apatinib in HCC treatment remai...

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Detalles Bibliográficos
Autores principales: Song, Jifu, Guan, Zhibin, Song, Chao, Li, Maojiang, Gao, Zhiwei, Zhao, Yongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047914/
https://www.ncbi.nlm.nih.gov/pubmed/33846786
http://dx.doi.org/10.3892/mmr.2021.12068