Retinal degeneration-3 protein promotes photoreceptor survival by suppressing activation of guanylyl cyclase rather than accelerating GMP recycling

Retinal degeneration-3 protein (RD3) deficiency causes photoreceptor dysfunction and rapid degeneration in the rd3 mouse strain and in human Leber’s congenital amaurosis, a congenital retinal dystrophy that results in early vision loss. However, the mechanisms responsible for photoreceptor death rem...

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Detalles Bibliográficos
Autores principales: Dizhoor, Alexander M., Olshevskaya, Elena V., Peshenko, Igor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047982/
https://www.ncbi.nlm.nih.gov/pubmed/33539922
http://dx.doi.org/10.1016/j.jbc.2021.100362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047982/
https://www.ncbi.nlm.nih.gov/pubmed/33539922
http://dx.doi.org/10.1016/j.jbc.2021.100362

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