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Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines

BACKGROUND: Human cancer cell line profiling and drug sensitivity studies provide valuable information about the therapeutic potential of drugs and their possible mechanisms of action. The goal of those studies is to translate the findings from in vitro studies of cancer cell lines into in vivo ther...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Umbach, David M., Krahn, Juno M., Shats, Igor, Li, Xiaoling, Li, Leping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048084/
https://www.ncbi.nlm.nih.gov/pubmed/33858332
http://dx.doi.org/10.1186/s12864-021-07581-7