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Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines
BACKGROUND: Human cancer cell line profiling and drug sensitivity studies provide valuable information about the therapeutic potential of drugs and their possible mechanisms of action. The goal of those studies is to translate the findings from in vitro studies of cancer cell lines into in vivo ther...
Autores principales: | Li, Yuanyuan, Umbach, David M., Krahn, Juno M., Shats, Igor, Li, Xiaoling, Li, Leping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048084/ https://www.ncbi.nlm.nih.gov/pubmed/33858332 http://dx.doi.org/10.1186/s12864-021-07581-7 |
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