Cargando…
Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
Prdm12 is a key transcription factor in nociceptor neurogenesis. Mutations of Prdm12 cause congenital insensitivity to pain (CIP) from failure of nociceptor development. However, precisely how deletion of Prdm12 during development or adulthood affects nociception is unknown. Here, we employ tissue-...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048104/ https://www.ncbi.nlm.nih.gov/pubmed/33789102 http://dx.doi.org/10.1016/j.celrep.2021.108913 |