Cyclosporine A and IFNγ licencing enhances human mesenchymal stromal cell potency in a humanised mouse model of acute graft versus host disease

Immunosuppressive ability in human MSC donors has been shown to be variable and may be a limiting factor in MSC therapeutic efficacy in vivo. The importance of cytokine activation of mesenchymal stromal cells (MSCs) to facilitate their immunosuppressive function is well established. This study sough...

Descripción completa

Detalles Bibliográficos
Autores principales: Corbett, Jennifer M., Hawthorne, Ian, Dunbar, Hazel, Coulter, Ivan, Chonghaile, Mairead Ni, Flynn, Catherine M., English, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048195/
https://www.ncbi.nlm.nih.gov/pubmed/33853687
http://dx.doi.org/10.1186/s13287-021-02309-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048195/
https://www.ncbi.nlm.nih.gov/pubmed/33853687
http://dx.doi.org/10.1186/s13287-021-02309-6

Ejemplares similares