Cyclosporine A and IFNγ licencing enhances human mesenchymal stromal cell potency in a humanised mouse model of acute graft versus host disease

Immunosuppressive ability in human MSC donors has been shown to be variable and may be a limiting factor in MSC therapeutic efficacy in vivo. The importance of cytokine activation of mesenchymal stromal cells (MSCs) to facilitate their immunosuppressive function is well established. This study sough...

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Detalles Bibliográficos
Autores principales: Corbett, Jennifer M., Hawthorne, Ian, Dunbar, Hazel, Coulter, Ivan, Chonghaile, Mairead Ni, Flynn, Catherine M., English, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048195/
https://www.ncbi.nlm.nih.gov/pubmed/33853687
http://dx.doi.org/10.1186/s13287-021-02309-6

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