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Pilot evaluation of an enzymatic assay for rapid measurement of antiretroviral drug concentrations

OBJECTIVE: Maintaining adequate drug adherence is crucial to ensure the HIV prevention benefits of pre-exposure prophylaxis (PrEP). We developed an enzymatic assay for rapidly measuring tenofovir-diphosphate (TFV-DP) concentrations—a metabolite that indicates long-term PrEP adherence. SETTING: The s...

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Detalles Bibliográficos
Autores principales: Olanrewaju, Ayokunle O., Sullivan, Benjamin P., Bardon, Ashley R., Lo, Tiffany J., Cressey, Tim R., Posner, Jonathan D., Drain, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048217/
https://www.ncbi.nlm.nih.gov/pubmed/33858461
http://dx.doi.org/10.1186/s12985-021-01543-x