LncRNA-Fendrr protects against the ubiquitination and degradation of NLRC4 protein through HERC2 to regulate the pyroptosis of microglia

OBJECTIVES: Targeted inhibition of inflammatory response can reduce diabetic cerebral ischemia–reperfusion (I/R) injure. Pyroptosis is characterized by caspase-1 dependence and the release of a large number of pro-inflammatory factors. LncRNA-Fendrr is associated with a variety of diseases, but Fend...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Li-Qing, Zheng, Yue-Ying, Zhou, Heng-Jun, Zhang, Xiong-Xin, Wu, Pin, Zhu, Sheng-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048261/
https://www.ncbi.nlm.nih.gov/pubmed/33858325
http://dx.doi.org/10.1186/s10020-021-00299-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048261/
https://www.ncbi.nlm.nih.gov/pubmed/33858325
http://dx.doi.org/10.1186/s10020-021-00299-y

Ejemplares similares