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LncRNA-Fendrr protects against the ubiquitination and degradation of NLRC4 protein through HERC2 to regulate the pyroptosis of microglia

OBJECTIVES: Targeted inhibition of inflammatory response can reduce diabetic cerebral ischemia–reperfusion (I/R) injure. Pyroptosis is characterized by caspase-1 dependence and the release of a large number of pro-inflammatory factors. LncRNA-Fendrr is associated with a variety of diseases, but Fend...

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Detalles Bibliográficos
Autores principales:	Wang, Li-Qing, Zheng, Yue-Ying, Zhou, Heng-Jun, Zhang, Xiong-Xin, Wu, Pin, Zhu, Sheng-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048261/ https://www.ncbi.nlm.nih.gov/pubmed/33858325 http://dx.doi.org/10.1186/s10020-021-00299-y

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