TNF-α acutely enhances acid-sensing ion channel currents in rat dorsal root ganglion neurons via a p38 MAPK pathway

BACKGROUND: Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine involved in pain processing and hypersensitivity. It regulates not only the expression of a variety of inflammatory mediators but also the functional activity of some ion channels. Acid-sensing ion channels (ASICs), as key se...

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Detalles Bibliográficos
Autores principales: Wei, Shuang, Qiu, Chun-Yu, Jin, Ying, Liu, Ting-Ting, Hu, Wang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048296/
https://www.ncbi.nlm.nih.gov/pubmed/33853615
http://dx.doi.org/10.1186/s12974-021-02151-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048296/
https://www.ncbi.nlm.nih.gov/pubmed/33853615
http://dx.doi.org/10.1186/s12974-021-02151-w

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