Coupling sparse Cox models with clustering of longitudinal transcriptomics data for trauma prognosis

BACKGROUND: Longitudinal gene expression analysis and survival modeling have been proved to add valuable biological and clinical knowledge. This study proposes a novel framework to discover gene signatures and patterns in a high-dimensional time series transcriptomics data and to assess their associ...

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Detalles Bibliográficos
Autores principales: Constantino, Cláudia S., Carvalho, Alexandra M., Vinga, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048345/
https://www.ncbi.nlm.nih.gov/pubmed/33853663
http://dx.doi.org/10.1186/s13040-021-00257-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048345/
https://www.ncbi.nlm.nih.gov/pubmed/33853663
http://dx.doi.org/10.1186/s13040-021-00257-8

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