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Coupling sparse Cox models with clustering of longitudinal transcriptomics data for trauma prognosis
BACKGROUND: Longitudinal gene expression analysis and survival modeling have been proved to add valuable biological and clinical knowledge. This study proposes a novel framework to discover gene signatures and patterns in a high-dimensional time series transcriptomics data and to assess their associ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048345/ https://www.ncbi.nlm.nih.gov/pubmed/33853663 http://dx.doi.org/10.1186/s13040-021-00257-8 |