Novel targetable FGFR2 and FGFR3 alterations in glioblastoma associate with aggressive phenotype and distinct gene expression programs

Prognostic molecular subgrouping of glioblastoma is an ongoing effort and the current classification includes IDH-wild-type and IDH-mutant entities, the latter showing significantly better prognosis. We performed a comparative integrated analysis of the FGFR glioblastoma subgroup consisting of 5 cas...

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Detalles Bibliográficos
Autores principales: Georgescu, Maria-Magdalena, Islam, Mohammad Zahidul, Li, Yan, Traylor, James, Nanda, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048363/
https://www.ncbi.nlm.nih.gov/pubmed/33853673
http://dx.doi.org/10.1186/s40478-021-01170-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048363/
https://www.ncbi.nlm.nih.gov/pubmed/33853673
http://dx.doi.org/10.1186/s40478-021-01170-1

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