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Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

ABSTRACT: Muscle-invasive bladder cancers are characterized by their distinct expression of luminal and basal genes, which could be used to predict key clinical features such as disease progression and overall survival. Transcriptionally, FOXA1, GATA3, and PPARG are shown to be essential for luminal...

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Detalles Bibliográficos
Autores principales: Iyyanki, Tejaswi, Zhang, Baozhen, Wang, Qixuan, Hou, Ye, Jin, Qiushi, Xu, Jie, Yang, Hongbo, Liu, Tingting, Wang, Xiaotao, Song, Fan, Luan, Yu, Yamashita, Hironobu, Chien, Ruby, Lyu, Huijue, Zhang, Lijun, Wang, Lu, Warrick, Joshua, Raman, Jay D., Meeks, Joshua J., DeGraff, David J., Yue, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048365/
https://www.ncbi.nlm.nih.gov/pubmed/33858483
http://dx.doi.org/10.1186/s13059-021-02325-y