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Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease

BACKGROUND: Glucocerebrosidase gene mutations are a common genetic risk factor for Parkinson's disease. They exhibit incomplete penetrance. The objective of the present study was to measure microglial activation and dopamine integrity in glucocerebrosidase gene mutation carriers without Parkins...

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Detalles Bibliográficos
Autores principales: Mullin, Stephen, Stokholm, Morten Gersel, Hughes, Derralyn, Mehta, Atul, Parbo, Peter, Hinz, Rainer, Pavese, Nicola, Brooks, David J., Schapira, Anthony H.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048428/
https://www.ncbi.nlm.nih.gov/pubmed/33278043
http://dx.doi.org/10.1002/mds.28375