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Disruption of circadian timing increases synaptic inhibition and reduces cholinergic responsiveness in the dentate gyrus

We investigated synaptic mechanisms in the hippocampus that could explain how loss of circadian timing leads to impairments in spatial and recognition memory. Experiments were performed in hippocampal slices from Siberian hamsters (Phodopus sungorus) because, unlike mice and rats, their circadian rh...

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Detalles Bibliográficos
Autores principales: McMartin, Laura, Kiraly, Marianna, Heller, H. Craig, Madison, Daniel V., Ruby, Norman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048473/
https://www.ncbi.nlm.nih.gov/pubmed/33439521
http://dx.doi.org/10.1002/hipo.23301