Driving CARs with alternative navigation tools – the potential of engineered binding scaffolds

T cells that are genetically engineered to express chimeric antigen receptors (CAR T cells) have shown impressive clinical efficacy against B‐cell malignancies. In contrast to these highly potent CD19‐targeting CAR T cells, many of those directed against other tumor entities and antigens currently s...

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Detalles Bibliográficos
Autores principales: Zajc, Charlotte U., Salzer, Benjamin, Taft, Joseph M., Reddy, Sai T., Lehner, Manfred, Traxlmayr, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
State‐of‐the‐Art Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048499/
https://www.ncbi.nlm.nih.gov/pubmed/32794303
http://dx.doi.org/10.1111/febs.15523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048499/
https://www.ncbi.nlm.nih.gov/pubmed/32794303
http://dx.doi.org/10.1111/febs.15523

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