Do Docking Sites Persist Upon Fluorination? The Diadamantyl Ether‐Aromatics Challenge for Rotational Spectroscopy and Theory

Fluorinated derivatives of biological molecules have proven to be highly efficient at modifying the biological activity of a given protein through changes in the stability and the kind of docking interactions. These interactions can be hindered or facilitated based on the hydrophilic/hydrophobic cha...

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Detalles Bibliográficos
Autores principales: Quesada‐Moreno, María Mar, Pinacho, Pablo, Pérez, Cristóbal, Šekutor, Marina, Schreiner, Peter R., Schnell, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048501/
https://www.ncbi.nlm.nih.gov/pubmed/33512017
http://dx.doi.org/10.1002/chem.202100078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048501/
https://www.ncbi.nlm.nih.gov/pubmed/33512017
http://dx.doi.org/10.1002/chem.202100078

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