Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient‐Derived Neurons

BACKGROUND: VPS35 is part of the retromer complex and is responsible for the trafficking and recycling of proteins implicated in autophagy and lysosomal degradation, but also takes part in the degradation of mitochondrial proteins via mitochondria‐derived vesicles. The p.D620N mutation of VPS35 caus...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanss, Zoé, Larsen, Simone B., Antony, Paul, Mencke, Pauline, Massart, François, Jarazo, Javier, Schwamborn, Jens C., Barbuti, Peter A., Mellick, George D., Krüger, Rejko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Regular Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048506/
https://www.ncbi.nlm.nih.gov/pubmed/33142012
http://dx.doi.org/10.1002/mds.28365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048506/
https://www.ncbi.nlm.nih.gov/pubmed/33142012
http://dx.doi.org/10.1002/mds.28365

Ejemplares similares