Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

For the first time we have been able to employ enantiopure 1,2‐amino alcohols derived from abundant amino acids in C−C bond‐forming hydrogen‐borrowing alkylation reactions. These reactions are facilitated by the use of the aryl ketone Ph*COMe. Racemisation of the amine stereocentre during alkylation...

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Detalles Bibliográficos
Autores principales: Hall, Christopher J. J., Goundry, William R. F., Donohoe, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048514/
https://www.ncbi.nlm.nih.gov/pubmed/33561302
http://dx.doi.org/10.1002/anie.202100922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048514/
https://www.ncbi.nlm.nih.gov/pubmed/33561302
http://dx.doi.org/10.1002/anie.202100922

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