Exposure‐Response and Population Pharmacokinetic Analyses of a Novel Subcutaneous Formulation of Daratumumab Administered to Multiple Myeloma Patients

We report the population pharmacokinetic (PK) and exposure‐response analyses of a novel subcutaneous formulation of daratumumab (DARA) using data from 3 DARA subcutaneous monotherapy studies (PAVO Part 2, MMY1008, COLUMBA) and 1 combination therapy study (PLEIADES). Results were based on 5159 PK sam...

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Detalles Bibliográficos
Autores principales: Luo, Man (Melody), Usmani, Saad Z., Mateos, Maria‐Victoria, Nahi, Hareth, Chari, Ajai, San‐Miguel, Jesus, Touzeau, Cyrille, Suzuki, Kenshi, Kaiser, Martin, Carson, Robin, Heuck, Christoph, Qi, Ming, Zhou, Honghui, Sun, Yu‐Nien, Parasrampuria, Dolly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Exposure Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048619/
https://www.ncbi.nlm.nih.gov/pubmed/33145788
http://dx.doi.org/10.1002/jcph.1771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048619/
https://www.ncbi.nlm.nih.gov/pubmed/33145788
http://dx.doi.org/10.1002/jcph.1771

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