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Angiotensin‐converting enzyme open for business: structural insights into the subdomain dynamics

Angiotensin‐1‐converting enzyme (ACE) is a key enzyme in the renin–angiotensin–aldosterone and kinin systems where it cleaves angiotensin I and bradykinin peptides, respectively. However, ACE also participates in numerous other physiological functions, can hydrolyse many peptide substrates and has v...

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Detalles Bibliográficos
Autores principales: Cozier, Gyles E., Lubbe, Lizelle, Sturrock, Edward D., Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048788/
https://www.ncbi.nlm.nih.gov/pubmed/33067882
http://dx.doi.org/10.1111/febs.15601