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Non‐Carbohydrate Glycomimetics as Inhibitors of Calcium(II)‐Binding Lectins

Because of the antimicrobial resistance crisis, lectins are considered novel drug targets. Pseudomonas aeruginosa utilizes LecA and LecB in the infection process. Inhibition of both lectins with carbohydrate‐derived molecules can reduce biofilm formation to restore antimicrobial susceptibility. Here...

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Detalles Bibliográficos
Autores principales: Kuhaudomlarp, Sakonwan, Siebs, Eike, Shanina, Elena, Topin, Jérémie, Joachim, Ines, da Silva Figueiredo Celestino Gomes, Priscila, Varrot, Annabelle, Rognan, Didier, Rademacher, Christoph, Imberty, Anne, Titz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048816/
https://www.ncbi.nlm.nih.gov/pubmed/33314528
http://dx.doi.org/10.1002/anie.202013217