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RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps

AIMS: RNF43 is suggested to be involved in the serrated pathway towards colorectal cancer and encodes a transmembrane Ring‐type E3 ubiquitin ligase that negatively regulates the Wnt pathway. This study aimed to elucidate the role of RNF43 gene variants in serrated polyposis syndrome (SPS) and serrat...

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Detalles Bibliográficos
Autores principales: van Herwaarden, Yasmijn J, Koggel, Lieke M, Simmer, Femke, Vink‐Börger, Elisa M., Dura, Polat, Meijer, Gerrit A, Nagengast, Fokko M, Hoogerbrugge, Nicoline, Bisseling, Tanya M, Nagtegaal, Iris D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048817/
https://www.ncbi.nlm.nih.gov/pubmed/33098683
http://dx.doi.org/10.1111/his.14286