Cargando…

Exome Sequencing of 21 Bardet‐Biedl Syndrome (BBS) Genes to Identify Obesity Variants in 6,851 American Indians

OBJECTIVE: In an ongoing effort to identify the genetic variation that contributes to obesity in American Indians, known Bardet–Biedl syndrome (BBS) genes were analyzed for an effect on BMI and leptin signaling. METHODS: Potentially deleterious variants (Combined Annotation Dependent Depletion score...

Descripción completa

Detalles Bibliográficos
Autores principales: Day, Samantha E., Muller, Yunhua L., Koroglu, Cigdem, Kobes, Sayuko, Wiedrich, Kim, Mahkee, Darin, Kim, Hye In, Van Hout, Cris, Gosalia, Nehal, Ye, Bin, Shuldiner, Alan R., Knowler, William C., Hanson, Robert L., Bogardus, Clifton, Baier, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048836/
https://www.ncbi.nlm.nih.gov/pubmed/33616283
http://dx.doi.org/10.1002/oby.23115