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The Sandarazols are Cryptic and Structurally Unique Plasmid‐Encoded Toxins from a Rare Myxobacterium
Herein, we describe a new plasmid found in Sandaracinus sp. MSr10575 named pSa001 spanning 209.7 kbp that harbors a cryptic secondary metabolite biosynthesis gene cluster (BGC). Activation of this BGC by homologous‐recombination‐mediated exchange of the native promoter sequence against a vanillate i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048970/ https://www.ncbi.nlm.nih.gov/pubmed/33534143 http://dx.doi.org/10.1002/anie.202014671 |