Cys–Cys and Cys–Lys Stapling of Unprotected Peptides Enabled by Hypervalent Iodine Reagents

Easy access to a wide range of structurally diverse stapled peptides is crucial for the development of inhibitors of protein‐protein interactions. Herein, we report bis‐functional hypervalent iodine reagents for two‐component cysteine‐cysteine and cysteine‐lysine stapling yielding structurally diver...

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Detalles Bibliográficos
Autores principales: Ceballos, Javier, Grinhagena, Elija, Sangouard, Gontran, Heinis, Christian, Waser, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048981/
https://www.ncbi.nlm.nih.gov/pubmed/33450121
http://dx.doi.org/10.1002/anie.202014511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048981/
https://www.ncbi.nlm.nih.gov/pubmed/33450121
http://dx.doi.org/10.1002/anie.202014511

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