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Scanning Protein Surfaces with DNA‐Encoded Libraries

Understanding the ligandability of a target protein, defined as the capability of a protein to bind drug‐like compounds on any site, can give important stimuli to drug‐development projects. For instance, inhibition of protein–protein interactions usually depends on the identification of protein surf...

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Detalles Bibliográficos
Autores principales: Kunig, Verena B. K., Potowski, Marco, Klika Škopić, Mateja, Brunschweiger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048995/
https://www.ncbi.nlm.nih.gov/pubmed/33295694
http://dx.doi.org/10.1002/cmdc.202000869