Cargando…
Scanning Protein Surfaces with DNA‐Encoded Libraries
Understanding the ligandability of a target protein, defined as the capability of a protein to bind drug‐like compounds on any site, can give important stimuli to drug‐development projects. For instance, inhibition of protein–protein interactions usually depends on the identification of protein surf...
Autores principales: | Kunig, Verena B. K., Potowski, Marco, Klika Škopić, Mateja, Brunschweiger, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048995/ https://www.ncbi.nlm.nih.gov/pubmed/33295694 http://dx.doi.org/10.1002/cmdc.202000869 |
Ejemplares similares
-
Investigations Into Chemically Stabilized Four-Letter DNA for DNA-Encoded Chemistry
por: Potowski, Marco, et al.
Publicado: (2022) -
Chemically Stabilized DNA Barcodes for DNA‐Encoded Chemistry
por: Potowski, Marco, et al.
Publicado: (2021) -
Acid- and Au(i)-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures
por: Škopić, Mateja Klika, et al.
Publicado: (2017) -
TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics
por: Kunig, Verena B. K., et al.
Publicado: (2020) -
Towards DNA‐Encoded Micellar Chemistry: DNA‐Micelle Association and Environment Sensitivity of Catalysis
por: Klika Škopić, Mateja, et al.
Publicado: (2021)