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Nanoscale Amperometry Reveals that Only a Fraction of Vesicular Serotonin Content is Released During Exocytosis from Beta Cells

Recent work has shown that chemical release during the fundamental cellular process of exocytosis in model cell lines is not all‐or‐none. We tested this theory for vesicular release from single pancreatic beta cells. The vesicles in these cells release insulin, but also serotonin, which is detectibl...

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Detalles Bibliográficos
Autores principales: Hatamie, Amir, Ren, Lin, Dou, Haiqiang, Gandasi, Nikhil R., Rorsman, Patrik, Ewing, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049002/
https://www.ncbi.nlm.nih.gov/pubmed/33340209
http://dx.doi.org/10.1002/anie.202015902