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A MIF‐Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2

Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine and atypical chemokine with a key role in inflammatory diseases including atherosclerosis. Key atherogenic functions of MIF are mediated by noncognate interaction with the chemokine receptor CXCR2. The MIF N‐like loop comprisin...

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Detalles Bibliográficos
Autores principales: Krammer, Christine, Kontos, Christos, Dewor, Manfred, Hille, Kathleen, Dalla Volta, Beatrice, El Bounkari, Omar, Taş, Karin, Sinitski, Dzmitry, Brandhofer, Markus, Megens, Remco T. A., Weber, Christian, Schultz, Joshua R., Bernhagen, Jürgen, Kapurniotu, Aphrodite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049018/
https://www.ncbi.nlm.nih.gov/pubmed/33125165
http://dx.doi.org/10.1002/cbic.202000574