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Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients

Cefazolin is an antibiotic frequently used for perioperative prophylaxis. Data from healthy adults and pediatric surgery patients were pooled to refine a previously developed population pharmacokinetic (PK) model and to determine the optimal body weight cutoff for selecting fixed doses of either 1 o...

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Detalles Bibliográficos
Autores principales: Schmitz, Michael L., Rubino, Christopher M., Onufrak, Nikolas J., Martinez, Diana Valencia, Licursi, Diane, Karpf, Angela, Cetnarowski, Wes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049034/
https://www.ncbi.nlm.nih.gov/pubmed/33202066
http://dx.doi.org/10.1002/jcph.1785