Progression of basal ganglia pathology in heterozygous Q175 knock‐in Huntington's disease mice

We used behavioral testing and morphological methods to detail the progression of basal ganglia neuron type‐specific pathology and the deficits stemming from them in male heterozygous Q175 mice, compared to age‐matched WT males. A rotarod deficit was not present in Q175 mice until 18 months, but inc...

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Detalles Bibliográficos
Autores principales: Deng, Yunping, Wang, Hongbing, Joni, Marion, Sekhri, Radhika, Reiner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049038/
https://www.ncbi.nlm.nih.gov/pubmed/32869871
http://dx.doi.org/10.1002/cne.25023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049038/
https://www.ncbi.nlm.nih.gov/pubmed/32869871
http://dx.doi.org/10.1002/cne.25023

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