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Progression of basal ganglia pathology in heterozygous Q175 knock‐in Huntington's disease mice
We used behavioral testing and morphological methods to detail the progression of basal ganglia neuron type‐specific pathology and the deficits stemming from them in male heterozygous Q175 mice, compared to age‐matched WT males. A rotarod deficit was not present in Q175 mice until 18 months, but inc...
Autores principales: | Deng, Yunping, Wang, Hongbing, Joni, Marion, Sekhri, Radhika, Reiner, Anton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049038/ https://www.ncbi.nlm.nih.gov/pubmed/32869871 http://dx.doi.org/10.1002/cne.25023 |
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