Synthesis and Evaluation of Novel Ring‐Strained Noncanonical Amino Acids for Residue‐Specific Bioorthogonal Reactions in Living Cells

Bioorthogonal reactions are ideally suited to selectively modify proteins in complex environments, even in vivo. Kinetics and product stability of these reactions are crucial parameters to evaluate their usefulness for specific applications. Strain promoted inverse electron demand Diels–Alder cycloa...

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Detalles Bibliográficos
Autores principales: Reinkemeier, Christopher D., Koehler, Christine, Sauter, Paul F., Shymanska, Nataliia V., Echalier, Cecile, Rutkowska, Anna, Will, David W., Schultz, Carsten, Lemke, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049044/
https://www.ncbi.nlm.nih.gov/pubmed/33577120
http://dx.doi.org/10.1002/chem.202100322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049044/
https://www.ncbi.nlm.nih.gov/pubmed/33577120
http://dx.doi.org/10.1002/chem.202100322

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