Increased protein propionylation contributes to mitochondrial dysfunction in liver cells and fibroblasts, but not in myotubes

Post‐translational protein modifications derived from metabolic intermediates, such as acyl‐CoAs, have been shown to regulate mitochondrial function. Patients with a genetic defect in the propionyl‐CoA carboxylase (PCC) gene clinically present symptoms related to mitochondrial disorders and are char...

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Detalles Bibliográficos
Autores principales: Lagerwaard, Bart, Pougovkina, Olga, Bekebrede, Anna F., te Brinke, Heleen, Wanders, Ronald J.A., Nieuwenhuizen, Arie G., Keijer, Jaap, de Boer, Vincent C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Mitochondrial Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049071/
https://www.ncbi.nlm.nih.gov/pubmed/32740932
http://dx.doi.org/10.1002/jimd.12296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049071/
https://www.ncbi.nlm.nih.gov/pubmed/32740932
http://dx.doi.org/10.1002/jimd.12296

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