Zinc Increases ABCA1 by Attenuating Its Clearance Through the Modulation of Calmodulin Activity

Aim: We previously revealed that Ca(++)-activated calmodulin binds to ABCA1 by the region near the PEST sequence and retards its calpain-mediated degradation to increase HDL biogenesis. Calmodulin activity is reportedly modulated also by other nutritional divalent cations; thus, we attempted to dete...

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Detalles Bibliográficos
Autores principales: Lu, Rui, Ishikawa, Takahiro, Tanaka, Mamoru, Tsuboi, Tomoe, Yokoyama, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049148/
https://www.ncbi.nlm.nih.gov/pubmed/32581187
http://dx.doi.org/10.5551/jat.55384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049148/
https://www.ncbi.nlm.nih.gov/pubmed/32581187
http://dx.doi.org/10.5551/jat.55384

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