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Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide
Post-translational modifications are often detected in age-related diseases associated with protein misfolding such as cataracts from aged lenses. One of the major post-translational modifications is the isomerization of aspartate residues (L-isoAsp), which could be non-enzymatically and spontaneous...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049310/ https://www.ncbi.nlm.nih.gov/pubmed/33857260 http://dx.doi.org/10.1371/journal.pone.0250277 |