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ORN: Inferring patient-specific dysregulation status of pathway modules in cancer with OR-gate Network
Pathway level understanding of cancer plays a key role in precision oncology. However, the current amount of high-throughput data cannot support the elucidation of full pathway topology. In this study, instead of directly learning the pathway network, we adapted the probabilistic OR gate to model th...
Autores principales: | Liang, Lifan, Zhu, Kunju, Tao, Junyan, Lu, Songjian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049496/ https://www.ncbi.nlm.nih.gov/pubmed/33819263 http://dx.doi.org/10.1371/journal.pcbi.1008792 |
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