Functional impact of cancer-associated cohesin variants on gene expression and cellular identity

Cohesin is a ring-shaped protein complex that controls dynamic chromosome structure. Cohesin activity is important for a variety of biological processes, including formation of DNA loops that regulate gene expression. The precise mechanisms by which cohesin shapes local chromosome structure and gene...

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Detalles Bibliográficos
Autores principales: Rittenhouse, Natalie L, Carico, Zachary M, Liu, Ying Frances, Stefan, Holden C, Arruda, Nicole L, Zhou, Junjie, Dowen, Jill M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049558/
https://www.ncbi.nlm.nih.gov/pubmed/33704438
http://dx.doi.org/10.1093/genetics/iyab025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049558/
https://www.ncbi.nlm.nih.gov/pubmed/33704438
http://dx.doi.org/10.1093/genetics/iyab025

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