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Dynein Harnesses Active Fluctuations of Microtubules for Faster Movement

The cytoskeleton forms a dynamic network that generates fluctuations larger than thermal agitation of the cytoplasm(1). Here, we tested whether dynein, a minus-end-directed microtubule (MT) motor(2), can harness energy from these fluctuations using optical trapping in vitro. We show that dynein form...

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Detalles Bibliográficos
Autores principales: Ezber, Yasin, Belyy, Vladislav, Can, Sinan, Yildiz, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049612/
https://www.ncbi.nlm.nih.gov/pubmed/33868446
http://dx.doi.org/10.1038/s41567-019-0757-4