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SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung

Extensive fibrin deposition in the lungs and altered levels of circulating blood coagulation proteins in COVID-19 patients imply local derangement of pathways that limit fibrin formation and/or promote its clearance. We examined transcriptional profiles of bronchoalveolar lavage fluid (BALF) samples...

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Detalles Bibliográficos
Autores principales: Mast, Alan E, Wolberg, Alisa S, Gailani, David, Garvin, Michael R, Alvarez, Christiane, Miller, J Izaak, Aronow, Bruce, Jacobson, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049742/
https://www.ncbi.nlm.nih.gov/pubmed/33683204
http://dx.doi.org/10.7554/eLife.64330