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miRNA-221 Regulates Spinal Cord Injury-Induced Inflammatory Response through Targeting TNF-α Expression

OBJECTIVES: To investigate the roles of miR-221 in spinal cord injury (SCI) as well as the underlying mechanism. METHODS: A mouse model of SCI was generated and used to examine dynamic changes in grip strength of the mouse upper and lower limbs. The expression of miR-221 and tumor necrosis factor-α...

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Detalles Bibliográficos
Autores principales: Sun, Feng, Zhang, Haiwei, Huang, Tianwen, Shi, Jianhui, Wei, Tianli, Wang, Yansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049790/
https://www.ncbi.nlm.nih.gov/pubmed/33928162
http://dx.doi.org/10.1155/2021/6687963