POU1F1 transcription factor induces metabolic reprogramming and breast cancer progression via LDHA regulation

Metabolic reprogramming is considered hallmarks of cancer. Aerobic glycolysis in tumors cells has been well-known for almost a century, but specific factors that regulate lactate generation and the effects of lactate in both cancer cells and stroma are not yet well understood. In the present study u...

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Detalles Bibliográficos
Autores principales: Martínez-Ordoñez, Anxo, Seoane, Samuel, Avila, Leandro, Eiro, Noemi, Macía, Manuel, Arias, Efigenia, Pereira, Fabio, García-Caballero, Tomas, Gómez-Lado, Noemi, Aguiar, Pablo, Vizoso, Francisco, Perez-Fernandez, Román
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049871/
https://www.ncbi.nlm.nih.gov/pubmed/33714987
http://dx.doi.org/10.1038/s41388-021-01740-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049871/
https://www.ncbi.nlm.nih.gov/pubmed/33714987
http://dx.doi.org/10.1038/s41388-021-01740-6

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