Multimodal, label-free fluorescence and Raman imaging of amyloid deposits in snap-frozen Alzheimer’s disease human brain tissue

Alzheimer’s disease (AD) neuropathology is characterized by hyperphosphorylated tau containing neurofibrillary tangles and amyloid-beta (Aβ) plaques. Normally these hallmarks are studied by (immuno-) histological techniques requiring chemical pretreatment and indirect labelling. Label-free imaging e...

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Detalles Bibliográficos
Autores principales: Lochocki, Benjamin, Boon, Baayla D. C., Verheul, Sander R., Zada, Liron, Hoozemans, Jeroen J. M., Ariese, Freek, de Boer, Johannes F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050064/
https://www.ncbi.nlm.nih.gov/pubmed/33859370
http://dx.doi.org/10.1038/s42003-021-01981-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050064/
https://www.ncbi.nlm.nih.gov/pubmed/33859370
http://dx.doi.org/10.1038/s42003-021-01981-x

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