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Activation of creER recombinase in the mouse calvaria induces local recombination without effects on distant skeletal segments

Conditional creER-mediated gene inactivation or gene induction has emerged as a robust tool for studying gene functions in mouse models of tissue development, homeostasis, and regeneration. Here, we present a method to conditionally induce cre recombination in the mouse calvarial bone while avoiding...

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Detalles Bibliográficos
Autores principales: Hou, Jue, Lin, Charles P., Intini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050205/
https://www.ncbi.nlm.nih.gov/pubmed/33859263
http://dx.doi.org/10.1038/s41598-021-87611-2