Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression

Female mammals achieve dosage compensation by inactivating one of their two X chromosomes during development, a process entirely dependent on Xist, an X-linked long non-coding RNA (lncRNA). At the onset of X chromosome inactivation (XCI), Xist is up-regulated and spreads along the future inactive X...

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Detalles Bibliográficos
Autores principales: Cerase, Andrea, Young, Alexander N., Ruiz, Nerea Blanes, Buness, Andreas, Sant, Gabrielle M., Arnold, Mirjam, Di Giacomo, Monica, Ascolani, Michela, Kumar, Manish, Hierholzer, Andreas, Trigiante, Giuseppe, Marzi, Sarah J., Avner, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050208/
https://www.ncbi.nlm.nih.gov/pubmed/33859315
http://dx.doi.org/10.1038/s42003-021-01945-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050208/
https://www.ncbi.nlm.nih.gov/pubmed/33859315
http://dx.doi.org/10.1038/s42003-021-01945-1

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