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New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D(2) receptor regulation and signaling
The dopamine D(2) receptor (D(2)R) is the target of drugs used to treat the symptoms of Parkinson’s disease and schizophrenia. The D(2)R is regulated through its interaction with and phosphorylation by G protein receptor kinases (GRKs) and interaction with arrestins. More recently, D(2)R arrestin-me...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050214/ https://www.ncbi.nlm.nih.gov/pubmed/33859231 http://dx.doi.org/10.1038/s41598-021-87417-2 |