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Induction of Exaggerated Cytokine Production in Human Peripheral Blood Mononuclear Cells by a Recombinant SARS-CoV-2 Spike Glycoprotein S1 and Its Inhibition by Dexamethasone

An understanding of the pathological inflammatory mechanisms involved in SARS-CoV-2 virus infection is necessary in order to discover new molecular pharmacological targets for SARS-CoV-2 cytokine storm. In this study, the effects of a recombinant SARS-CoV-2 spike glycoprotein S1 was investigated in...

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Detalles Bibliográficos
Autores principales: Olajide, Olumayokun A., Iwuanyanwu, Victoria U., Lepiarz-Raba, Izabela, Al-Hindawi, Alaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8050229/
https://www.ncbi.nlm.nih.gov/pubmed/33860869
http://dx.doi.org/10.1007/s10753-021-01464-5